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Vitamin Deficiency Diseases
VITAMIN E
The term vitamin E describes a family of 8 antioxidants, 4 tocopherols (α,β,γ, &,δ) and4 tocotrienols.
α-tocopherol is the active form of vitamin E in the human body.
FUNCTIONS
• The primary function of vitamin E is antioxidant. It intercepts free radicals & prevents the destruction of the cell membranes.
• It protects the fat in LDL from oxidation.
• It inhibits platelet aggregation.
• It enhances vasodilatation.
• It inhibits the activity of protein kinase C.
Vitamin E Dietary Sources
Vegetable oils
Almonds & peanuts
Avocado
Spinach
Carrots (least)
Vitamin E deficiency
•Severe vitamin E deficiency causes Neurological symptoms (impaired coordination) & muscle weakness.
Increased risk of cardiovascular diseases
Hemolytic anaemia in children
RISK FACTORS
Severe PEM
Genetic defects affecting the transfer protein of α-tocopherol
Fat malabsorption syndrome
THERAPEUTIC USES
Prevention of cardiovascular diseases
Diabetes Mellitus
Cancer prevention
Boost immunity
Dementia
TOXICITY
Excess vitamin E may cause 9 Impaired blood clotting leading to an increased risk of bleeding in some persons.
9It is recommended that vitamin E supplements to be stopped one month before elective surgery.
VITAMIN K
The K is derived from the German word Coagulation.
There are 2 naturally occurring forms of vitamin K. Plants synthesize phylloquinone (vitamin K1) & bacteria synthesize menaquinone-3 (Vit K2).
Menaquinone-4 is produced in animals from vit K1, but its function is yet to be discovered.
| Author | – |
| Language | English |
| No. of Pages | 30 |
| PDF Size | 3 MB |
| Category | Education |
| Source/Credits | drive.google.com |
Vitamins And Their Deficiency Diseases PDF Free Download